Articles
Yu. S. Rudyk, S. M. Pyvovar, T. V. Lozyk, V.Yu. Galchinskaya, T.O.Chenchik. THE SYNDROME "LOW TRIIODOTHYRONINE" AND A COURSE A HEART FAILURE Georgian Medical News. 2019;4(289):79-85.
The effect of the “low triiodothyronin syndrome” (LT3S) (according to the criterion of T3f ≤ 2 pmol / l) on the course of heart failure (HF) was studied. The biennial study included 157 patients with HF (with a history of myocardial infarction…
Read MoreS. M. Pyvovar, Yu. S. Rudyk, T. V. Lozyk, V. Yu. Halchinska, T. O. Chenchyk. The features of “low T3” syndrome definition in a heart failure and its effect on a course of the disease. Zaporozhye medical journal. 2019, Volume 21. No. 4, 437-443
Серцева недостатність (СН) – є актуальною проблемою у зв’язку з високою смертністю хворих. Розуміння патофізіологічних механізмів СН важливо при оптимізації схем терапії. Синдром «низького трийодтироніну» (СНТ3) спостерігається у частини хворих з СН…
Read MoreYu.S.Rudyk, S.N.Pyvovar, T.M.Bondar, T.V.Lozyk. Some aspects of the impact of gene polymorphism beta1-adrenergic receptors on the course of heart failure. Journal amnu. 2019;25(2):139-48.
Chronic β1- adrenergic receptors activation is implicated in the pathogenesis of HF and β-adrenergic receptors blockade improves survival in left ventricular systolic dysfunction. The individual approach to HF patients, which based on gene β-…
Read MorePyvovar S.M., Rudyk Yu.S., Lozyk T.V., Galchinska V.Yu. Polymorphism of C825T (RS5443) G-protein beta3-subunit gene and the long-term prognosis for patients with heart failure. World of medicine and biology. 2019;1(67):88-93.
Forecasting of an unfavorable course in heart failure is very relevant. The purpose of the work was to determine the effect of the G protein β3-subunit C825T (RS5443) gene polymorphism on the long-term prognosis for patients with heart failure. The…
Read MorePyvovar S, Rudyk Yr, Kravchenko I, Lozyk T. The long-term forecast of patients with heart failure and the gene polymorphism gln27glu of β2-adrenoreceptors. ScienceRise. Medical Science. 2018;6(26):4-10.
The aim: to determine the influence of Gln27Glu polymorphism of the β2 -adrenergic receptor gene on the longterm prognosis of patients with heart failure. Material and methods. The study included 200 patients with heart failure. The clinical course…
Read MorePyvovar S.M. INFLUENCE OF COMBINATION OF GENETIC HAPLOTYPE OF β1- AND β2-ADRENOEPECTEPTORS ON CARDIAC DISEASE. Ukrainian therapeutic journal. 2018;3-4:48-55.
The objective: To determine the prevalence and the effect of combined haplotypes of β1- and β2-adrenergic receptor genes on the course of heart failure. Materials and methods. 200 patients with heart failure were included to study. The clinical…
Read MorePyvovar S.M. The Syndrome Of "Low T3" And Its Frequency With Heart Failure. UKRAINIAN THERAPEUTIC JOURNAL. 2018;1: 46-51.
The objective: to study the frequency of the syndrome of "Low T3" in patients with decompensated heart failure (HF) on admission and its effect on the course of the disease. Materials and methods. 188 patients with HF were included to the study (73…
Read MorePyvovar S.N. Dependence of the current of heart failure on the Gln27Glu polymorphism of the beta 2-adrenoreceptor gene. Ukrainian therapeutic journal. 2016; 3: 50-55.
There are dates of the impact of a polymorphismof b2-adrenergic-receptors on cardiovascular diseases in an article. The polymorphism b2-adrenergic-receptors Arg16 has a protective influence on cardiovascular diseases. The…
Read MorePyvovar S.N., Rudyk Y.S., Beletskaja O.M. The cardioprotective mechanisms of thyroid hormones. Ukrainian Therapeutical Journal. 2013. 3. 95-102
The heart failure represents the final common outcome in cardiovascular diseases. Despite significant therapeutic advances, morbidity and mortality of heart failure remain unacceptably high. Heart failure is preceded and sustained by a process of…
Read MoreRudyk Y.S., Pyvovar S.N. The applied value of pharmacogenetics in the treatment of patients with heart failure. Ukrainian Therapeutical Journal. 2013. N 1. С. 84-92.
The article highlights some of the discoveries in the field of genetics. These innovations are determined by the new level of development of a medicine. The standard approach to the organization of patient care is not always effective. The…
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